S Harshavardhana was born in New Delhi in 1958.

He is a Post Graduate in a Biosciences from Birla Institute of Science & Technology, Pilani and has a Diploma in Business Management.

Harshavardhana is a self-taught artist.

He has had several solo exhibitions:
In 1997, 1999, 2007 and 2012 he exhibited solo in New Delhi. In 2000 he had a solo show at Lakeeren Art Gallery, Mumbai. In 2006 he exhibited ‘Acute, Obtuse and Sometimes Right’ at Aicon Gallery, Palo Alto and in 2007 he exhibited at Aicon Gallery, New York. In 2007 he had a solo exhibition at Indigo Blue Art in Singapore. In 2014 he exhibited solo at Galerie J.Bastien Art in Brussels.

In 2004 he participated in a two-person exhibition with Manish Pushkale at Bodhi Art, Singapore and in 2006 with Sheetal Gattani at Galerie Muller and Plate in Berlin.

He has participated in several group exhibitions:

In 1996, 1998, 1999, 2000, 2002, 2003, 2004, 2006, 2009 and 2010 he participated in many group exhibitions in Mumbai, New Delhi and Kolkata. In 1997 he participated in Post Modern Indian Art at Turlock in CA, USA. In 1998 he took apart in Veiled Spaces at Jehangir Art Gallery, Mumbai. In 2003 he participated in 2D/3D at Visual Arts Centre, Hong Kong. In 2006 he took part in Confluence at Aicon Gallery, New York. In 2007 he participated in Colors of Art at Jehangir Art Gallery, Mumbai. In 2009 he took part in Think Small at Art Alive Gallery, New Delhi and participated in 'Moderns and More' at Aicon Gallery, Palo Alto. In 2010  and 2011 he participated in group shows in Mumbai, New Delhi and Gurgaon. In 2012 he took part in ‘Aviraam: Celebrating the Pioneer Spirit- S. H. Raza at 90', presented by The Raza Foundation at Visual Arts Gallery, India Habitat Centre in New Delhi.

Harshavardhana lives and works in New Delhi.