Seema Kohli was born in 1960 in New Delhi.

In 1981 she received her degree in Bachelor of Arts in Philosophy from Miranda House at Delhi University, New Delhi. In 1983 she received her Diploma in Applied Arts (ITI) from South Delhi Polytechnic, New Delhi.

Seema had several solo shows:
In 1998 she exhibited solo at AIFACS in New Delhi. In 1999 she had a solo, Spirited Sprite at Triveni Gallery, New Delhi. In 1999 she showcased Reflections at Lalit Kala Akademi, New Delhi. In 2001, 2002, 2004, 2006 and 2007 she exhibited Hiranya Garbha: The Golden Womb at ISU Art Gallery, Singapore; at Triveni Kala Sangam and Maurya Marriot, New Delhi; at Anayas Art Gallery, New Delhi; at Art Heritage, New Delhi; at Chor Bazaar in London; at Gallery Space, Hyderabad and at India Habitat Centre, New Delhi. In 2002 and 2003 she exhibited Random Introspection at Maurya Marriot and The Grand, New Delhi. In 2007 she exhibited solo at Art Room, New Delhi. In 2009 she exhibited A Philosophical Fantasy at Gallery Art and Soul, Mumbai. In 2009 she had a solo exhibition, Mystical Narratives at Mahua Art Gallery, Bangalore. In 2009 she showcased solo, Swayam Sidha: Myth, Mind and Movement at Lalit Kala Akademi, New Delhi. In 2010 she exhibited Myth is Reality at Gallery Art and Soul, Mumbai. In 2011 she exhibited Synchronicity at Jain Marunouchi Gallery, New York.

Seema participated in several group shows:
In 1997 she took part in a group exhibition at Sahitya Kala Parishad, Rabindra Bhawan, New Delhi. In 1999 and 2000 she participated in group shows at Birla Academy of Art and Culture, Kolkata; at CPLA and at Hotel Intercontinental, New Delhi. In 2000 and 2001 she took part in the Annual exhibition of AIFACS, New Delhi. In 2001 she participated in various group exhibitions in New Delhi: at Habitat Centre; at Swastika Gallery; at Academy of Fine Arts and Literature; at Russian Centre; at Studio 55 and at Masters Guild. In 2001 she participated in group shows at ISU Art Gallery, Singapore and Sir Vincent Gallery, Bangalore. In 2003 she took part in the Annual Exhibition of Drawing and Photography at Sahitya Kala Parishad, New Delhi. In 2002 - 2011 she took part in various group shows in New Delhi, Haryana, Bhopal, Bangalore, Mumbai and Chennai. In 2005 she exhibited Journey Through Line Color and Images at Lalit Kala Akademi, New Delhi. In 2006 and 2007 she exhibited Devotion at India Habitat Centre, New Delhi. In 2006 she took part in Visual Dialogue at Jehangir Art Gallery, Mumbai and participated in Seven Women Artists Show at Bharat Bhavan, Bhopal. In 2007 she participated in Fact and Fiction at SW1 Gallery, London. In 2007 and 2008 she participated in the National Exhibition at Lalit Kala Akademi, New Delhi. In 2008 she participated in Subliminal Messages at Indigo Art, Singapore; took part in a group show at AICON Gallery, London and took part in a group show at Sovereign Art Foundation, Hong Kong. In 2009 she took part in Transcending Boundaries at The Nehru Centre, London; she participated in 'SAsia' at The Shore Institute of The Contemporary Arts (SICA), New Jersey; she participated in the Florence Biennale, Florence and took part in a group show at ARCOmadrid, Spain. In 2009 she took part in Satyagraha at Casa India, Valladolid in Spain and exhibited in a group show at Art Basel, Switzerland. In 2010 she participated in Holy Now at Gallery 27, London and she participated in Roots in the Contemporary at Kamalnayan Bajaj Art Gallery, Mumbai. In 2011 she took part in The Lost Sparrow at Visual Art Gallery, India Habitat Centre in New Delhi; she participated in Melange at The Harrington Street Arts Centre, Kolkata and she took part in Goddess, Lion, Peasant, Priest: Modern and Contemporary Indian Art at Museum Oglethorpe, Atlanta. In 2012 she took part in Women: Sacred and the Temporal at Shrishti Art Gallery, Hyderabad.

In 2008 she received the Lalit Kala Akademi Award for Women Achievers in Contemporary Indian Art in New Delhi.

Seema lives and works in New Delhi.